Researchers reveal how oral bacteria suppress protection against viral growth

Researchers from the University of Louisville School of Dentistry and their colleagues have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection. A family of proteins known […]

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Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’

Recent guidelines have restricted aspirin use in the primary prevention of cardiovascular disease to patients under 70, and more recent guidance to patients under 60. Yet, the risks of heart attacks and strokes increase markedly with age. There has been considerable confusion from recently reported results of four large-scale randomized trials of aspirin in high-risk […]

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How LPS prevents or promotes development of asthma and allergic disease

Immunologists have long been baffled by LPS, the bacterial lipopolysaccharide that helps form the cell walls of Gram-negative bacteria. Many experiments show that exposure to LPS during exposure to environmental allergens protects against developing asthma or allergic disease. Yet other numerous experiments show that the presence of LPS during exposure to environmental allergens does the […]

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The promise of repairing bones and tendons with human-made materials

Brittany Taylor is a biomedical engineer and assistant professor who studies novel ways to improve bone and tendon healing after injuries. She is exploring drug delivery systems and temporary artificial tissue replacements to promote healing of tendons and the interface with bones and muscle. Millions of musculoskeletal injuries each year cause pain and reduce people’s […]

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RNA sequencing from single blood draw can predict pregnancy health and preeclampsia

Imaging techniques such as ultrasound technologies and minimally invasive procedures are powerful tools for assessing pregnancy health and progression. However, a detailed, ongoing assessment of the well-being of the baby and placenta is difficult, and clinicians still lack tools to preemptively identify those at risk of pregnancy complications like preeclampsia, a leading cause of maternal […]

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